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The HIV Vaccine Trials Network is comprised of the HIV Vaccine Trials Units, Vaccine Leadership Group, Statistical and Data Center (SCHARP), and the Laboratory Program. We are sponsored by the National Institutes of Health (NIH).
We are a global network of medical research institutions referred to as HIV Vaccine Trials Units, or HVTUs. These sites are where testing of experimental HIV vaccines takes place. Through cooperative agreements with institutions worldwide, the National Institute of Allergy and Infectious Diseases (NIAID) provides resources to adequately test the safety and immunogenicity of promising vaccine candidates. The testing of candidate HIV/AIDS vaccines requires access to diverse populations for clinical trial participation and the availability of experienced staff, adequate space, and facilities.
View Map of HVTUs
Vaccine Leadership Group/Core
The Vaccine Leadership Group (VLG) Core Office coordinates all aspects of the HVTN and oversees the functions of the Laboratory Program and the Statistical and Data Management Center. Headquartered at the Fred Hutchinson Cancer Research Center in Seattle, Washington, the VLG Core Office is responsible for carrying out the HVTN's research agenda, including coordinating, administering and supporting the research activities of all US and international sites. The VLG Core Office also provides direct support to the Scientific Steering Committee, HVTN Science Committees, development teams and working groups, the Community Advisory Boards (CABs) and other functions as defined by the HVTN leadership.
SCHARP (Statistical Center for HIV/AIDS Research & Prevention)
The Statistical and Data Management Center provides the following:
Our laboratories perform tests of the body's immune responses that are consistent across HVTN protocols. These tests include measuring whether the body produces antibodies in response to the candidate vaccine (humoral response) and whether the body produces infection-fighting T-cells (cellular response). HVTN laboratories are located at:
The U.S. HIV testing lab is located at the University of Washington Virology Specialty Laboratory.