Dr. Kathy Mngadi, Principal Investigator
Tembisa CRS, Johannesburg, South Africa
Dr. Kathy Mngadi qualified as a medical practitioner at the Nelson Mandela School of Medicine in 1987. While working in a communicable diseases outpatient clinic in Durban, following a personal bout of Tuberculosis, she first encountered HIV and referred confirmed TB cases for HIV testing through an NGO, in the days when only venous blood samples were drawn and results took two weeks to get back. At that time no treatment was available for HIV, and the havoc wreaked by the disease in those co-infected with TB prompted her to take on the role of Medical Director at a local hospice where she was pivotal in opening admissions to HIV-infected patients for respite, end-of-life care, and treatment of opportunistic infections. She worked in the first ART programme in South Africa at the Anglogold Orkney Hospital clinic, where she was first exposed to HIV treatment research through the Aurum Institute. She later joined in their own PEPFAR-funded ART programme and eventually in HIV and TB prevention and treatment research at the Klerksdorp site, working on HVTN 503 among other protocols. She joined CAPRISA in Durban 7 years later, implementing HVTN 100, 107, 108, 702, and 703, and also serves as co-chair of HVTN 107 and HVTN 705/HPX2008. She sits on the Scientific Governance Committee, Protocol Committee, and Efficacy Trials Working Group. She recently re-joined the Aurum team in May 2018 as a CRS leader and PI for HVTN 705/HPX2008 at the Tembisa-Clinic 4 site. She enjoys the sense of community in the HVTN, the effort to build capacity among local investigators, and the strong Community Engagement programme promoted within the HVTN. She is determined to contribute to the collaborative efforts to find a safe and effective HIV vaccine.