70+
Study Sites
Headquartered at Fred Hutch in Seattle, the Network includes over 70 sites on four continents staffed by teams with expertise in vaccinology, immunology, and in conducting clinical trials.
100+
Clinical Trials
For more than 20 years, the HVTN has conducted all phases of clinical trials based on the latest developments in vaccinology and immunology for the prevention of HIV, tuberculosis and COVID-19.
95+
Scholar Awards
We are investing in the next generation of HIV prevention researchers with grants and mentoring for African American/Black, Hispanic/Latinx, Native American/American Indian/Alaska Native, Native Hawaiian, Asian and Pacific Islander medical students.
HVTN Mission
Our mission is to fully characterize the safety, immunogenicity, and efficacy of HIV vaccine candidates with the goal of developing a safe, effective vaccine as rapidly as possible for prevention of HIV globally.

Who We Are
We are the world’s largest publicly-funded international collaboration focused on the evaluation of vaccines to prevent HIV/AIDS.

What We Do
Our sites conduct all phases of clinical trials — from evaluating early phase vaccines for safety and immunogenicity to testing vaccine efficacy.

Get Involved
Worldwide, thousands of people have participated in HIV vaccine trials. Volunteers are the heroes of vaccine development.
It Takes a Village
The HIV Vaccine Trials Network is an international partnership of research scientists, clinical trial sites, laboratories, statisticians, regulators and ethicists, participants, volunteers and community representatives working with industry, academia, and governments in the global search for a preventive HIV vaccine.
Recent HVTN News & Announcements
A statement from the HVTN on the PrEPVacc study announcement
PrEPVacc announced that vaccinations have been stopped in its HIV Phase 2 prevention study of experimental vaccine regimens running in East and Southern Africa due to lack of demonstrated efficacy in preventing HIV acquisition.
The HVTN Mourns the Passing of Dr. Stephaun Elite Wallace
Dr. Wallace was a giant of a spokesperson for the HVTN; who conveyed a conviction; an optimism; a way of problem solving that was a model to all of us.
Read the Latest Community Compass Issue
In this issue, we highlight some of the critical topics relating to health equity from the HVTN Community, remember three longtime activists and community leaders who recently passed, and provide important updates from our partners.