Published Guides

Resources from the HVTN

HIV Incidence in Prevention Trial Control Groups and Observational Studies: A Summary Table (Excel file)

HIV vaccine clinical researchers depend on HIV incidence data to design, properly power, and conduct efficacy trials. Such data come from two main sources: Observational longitudinal cohorts in relevant populations, and placebo arms of past HIV prevention efficacy trials. The HVTN Efficacy Trials Working group, in collaboration with the HIV Vaccine Enterprise, created a reference table to help researchers synthesize the studies that may provide relevant incidence data. The table contains two main tabs, one listing efficacy trials and the other - observational studies. The table is intended to be used as a reference to identify studies that may have information useful for study design and statistical power calculations. The user is encouraged to refer to listed publications and other resources to get a better understanding of the context in which the incidence was observed. The table was last updated in 2019.

HIV Glossary of Terms

HIV Abbreviations & Acronyms

Information About HIV/AIDS Vaccines

• Global HIV Vaccine Enterprise
  An alliance of independent organizations dedicated to accelerating the development of a preventive HIV vaccine.
• International AIDS Vaccine Initiative (IAVI)
  IAVI is a global nonprofit organization funded through the private sector working to speed the search for vaccines to prevent HIV/AIDS.
• South African AIDS Vaccine Initiative (SAAVI)
  SAAVI was established to coordinate the research, development and testing of HIV/AIDS vaccine in South Africa.
• Vaccine Research Center (VRC)
  The Dale and Betty Bumpers Vaccine Research Center at National Institutes of Health is conducting cutting-edge research to develop vaccines against HIV, and recently discovered new broadly neutralizing antibodies against HIV.

Broad Information on HIV/AIDS and Prevention Efforts (Not Limited to Vaccines):

• AIDSinfo.nih.gov
  AIDSinfo is a service of the U.S. Department of Health & Human Services.
• AVAC: Global Advocacy for HIV Prevention
  Supports HIV/AIDS research, HIV prevention, treatment education, and the advocacy of sound AIDS-related public policy. They also sponsor the Advocates Network, which offers webinars and materials for community-based HIV prevention advocates.
  
• U.S. Centers for Disease Control and Prevention
  The US government's disease control and prevention agency.
• NAM: AIDSMAP
  A U.K.-based organization, the mission of AIDSMAP is to share knowledge and save lives. They often provide coverage of scientific conferences, including summaries of key findings for laypersons.
• National AIDS Trust
  NAT, a U.K.-based organization, aims to promote a wider understanding of HIV and AIDS.
• National Institute of Allergy and Infectious Diseases (NIAID)
  NIAID is the primary agency of the US government devoted to research on HIV/AIDS and the sponsor of the HIV Vaccine Trials Network.
• Office of HIV/AIDS Network Coordination (HANC)
  HANC works with the HIV/AIDS clinical trials networks funded by the Division of AIDS of the U.S. National Institutes of Health (NIH) with the intent of creating a more integrated, collaborative and flexible research structure.
• UNAIDS
  The Joint United Nations Programme on HIV/AIDS.
• What is PrEP?
  Pre-exposure prophylaxis, or PrEP, is the daily use of anti-HIV medication that keeps HIV negative people from becoming infected with HIV. So far only one pill, Truvada, has been approved for this use, but additional studies are in progress to find additional drugs that could be used, and other ways of taking them. This is an exciting new area in HIV prevention research
• PublicHealth 
  PublicHealth.org is dedicated to connecting patients, students and professionals to the latest and most useful healthcare information and resources available. 

Other HIV Prevention Networks Funded by NIAID

• HIV Prevention Trials Network (HPTN)
• International Maternal Pediatric Adolescent AIDS Clinical Trials Network (IMPAACT)

Resources From the NIAID Office of HIV/AIDS Network Coordination

• HIV/AIDS Network Coordination (HANC)
• Community Partners Training Materials 
• Recommendations for Community Engagement in HIV/AIDS Research Version 2.0
• Be the Generation HIV Prevention Research
• Basic Scientific Literacy (BSL) Training Module

HIV Prevention Email Lists

• AVAC Advocates Network
  (click on the link on this website to join the Advocates Network)
  The Advocates Network sends out periodic messages by e-mail. They offer webinars and conference calls to discuss current topics in HIV prevention, and often provide coverage of major HIV prevention conferences.