Examples of Data Projects
The HVTN has a wealth of data from completed HIV and Covid-19 vaccine trials available to analyze. Below are examples of projects that could be undertaken with currently existing data from prior HVTN trials.
- Compare the distributions of HIV vaccine insert distances to circulating strains across HVTN 505, 702, 705, 706, and RV144 to help interpret results of the 3 recent efficacy studies (HVTN 702, 705, 706) and explore the potential to improve vaccine insert selection.
Special requirement: Interest in bioinformatics and working with public viral sequence databases.|
- Explore the relationship between HIV vaccine reactogenicity and immune responses, focusing on HVTN 702 & 705.
Special requirement: Medical degree and/or familiarity with reactogenicity data.
- Estimate the prevalence and incidence of STIs in HVTN 702. Determine the association between time dependent STIs (syphilis, gonorrhea, chlamydia, and trichomonas) and HIV.
Special requirement: Interest and experience with STIs, basic understanding of epidemiology.
Other opportunities can be proposed by awardees, especially projects that align with an awardee’s area of interest, projects that allow an awardee to focus on a specific skill, or projects that include protocols with which awardees have been involved.